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Professor Adam Walker

Principal investigator

Adam has focused on uncovering the mechanisms of MND and FTD for over 15 years. He obtained his BSc(Hons) in biochemistry from the University of Tasmania, PhD in neuroscience from the University of Melbourne, and was a postdoctoral fellow at the Center for Neurodegenerative Disease Research at the University of Pennsylvania and at Macquarie University, Sydney before founding the lab as the Ross Maclean Fellow for MND Research at the Queensland Brain Institute (2018-2025). He is a Bill Guest FightMND Mid-Career Research Fellow (since 2022) and the Chair of Pharmacological Sciences, The University of Sydney (since 2024).

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Juliana Venturato

Laboratory manager

Juliana has used her wealth of experience in cell culture, biochemistry and molecular biology to study the molecular mechanisms of ALS and FTD, and to keep the lab running smoothly since 2018, at the Queensland Brain Institute at The University of Queensland and now also the Charles Perkins Centre at The University of Sydney. 

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Dr ADEKunle Bademosi

Race against dementia-dementia australia research foundation postdoctoral fellow

Kunle uses single-molecule imaging to study the normal and pathological role of TDP-43 in cells, at QBI. He completed his PhD at QBI investigating how general anaesthestics attenuate neuronal communication, and was a postdoctoral fellow at the Flanders Institute of Biotechnology (VIB), Belgium, investigating synaptic autophagy in Parkinson’s disease.

Dr Anna Harutyunyan

postdoctoral fellow

Dr Katie Robinson

postdoctoral fellow

Dr Matisse jacobs

PhD CANDIDATE (2021-2025)

Matisse employed CRISPR/Cas9 gene editing technology and high throughput microscopy to identify regulators of TDP-43 pathology and toxicity. Her PhD was conferred in 2025, from The University of Queensland.

Elise Kellett

PHD CANDIDATE

Elise is conducting studies to understand how pathology develops in neurons in ALS/FTD, supported by an MND Australia PhD scholarship, at The University of Queensland.

Natalie Clubley

PHD Student

Mu SHEEN Chang

ReSEARCH ASSISTANt

Mu Sheen undertook Honours in the lab at UQ in 2024-25, studying the role of non-neuronal cells and synaptic dysfunction in models of TDP-43 pathology, and continues as a research assistant at the Charles Perkins Centre.

Hao (Donny) Wu

Research Assistant

Donny applies a variety of bioinformatics pipelines to large datasets to reveal biological pathways involved in ALS and FTD, at The University of Queensland.

 
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Join us!

We are actively recruiting research students and staff members to join the lab at The University of Sydney.

Be in touch if you are interested to be involved in our research.

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Lab Alumni

 

Yi Jia (Celine) Chye

Research Assistant

Celine joined the lab as an undergraduate summer student in 2022, and completed Honours (First Class) in 2024 focused on models of TDP-43 pathology.

Dr Sean Keating

PhD CANDIDATE (2020-2025)

Sean employed gene editing technology to create new disease models, and investigated protein clearance pathways that contribute to degradation of pathological TDP-43. He received First Class Honours in the lab in 2019, and was conferred his PhD from The University of Queensland in 2025, supported by the Thornton Foundation and MND Australia.

Dr Wei (leon) luan

postdoctoral fellow (2020-2025)

Leon joined the lab in 2020 to study the role of cellular stress responses in disease and led several pre-clinical and proof-of-concept therapeutic studies.

Dr Rebecca San gil

Postdoctoral Fellow (2018-2025)

Bec joined the lab in 2018 and led projects to understand the role of TDP-43 in disease pathogenesis, and was awarded the FightMND Early Career Research Fellowship in 2020.

Dr Thomas Hedl

Masters Student, PhD Candidate (2018-2025)

Tom employed proteomics techniques to analyse the protein composition of neuronal pathology in MND and FTD. He undertook Masters of Research studies, followed by PhD.

Lidia Madrid

research assistant (2020-2024)

Lidia conducted a myriad of studies to test potential therapeutics and characterise new models of ALS/FTD.

 

DR Heledd Brown-Wright

postdoctoral Fellow (2019-2024)

Heledd led pre-clinical and disease modelling projects focused on gene therapy and virus-mediated approaches.

Louis See Han Lim

Winter Student, Masters Student (2024)

Louis studied the role of non-neuronal cells in ALS/MND, employing biochemical and histological techniques, completing a Masters in Medical Biotechnology.

Christopher Hau

Summer Student, Masters Student (2024)

Christopher performed bioinformatics analysis of datasets from TDP-43 models to identify altered biological pathways, completing a Masters of Bioinformatics in 2024.

Sarah risby-Jones

Honours Student (2023)

Sarah joined the lab as an undergraduate summer student in 2021, and returned to complete Honours (First Class) to identify genes that modulate protein aggregation in ALS.

 

yvonne Un

Honours Student (2023)

Yvonne joined the lab as an undergraduate summer student in 2022 and continued on with Honours (First Class, University Medal), using biochemical and microscopy techniques to study TDP-43 pathology.

Dr Purba Nag

senior research assistant (2022-23)

Purba worked on projects aimed at understanding genes and proteins that control protein aggregation in neurodegeneration, using cell and human iPSC-derived neuron models of disease.

yi KIt chui

Honours student (2022)

Kit was an undergraduate winter intership student, and returned for Honours, employing adeno-associated virus approaches to study proteins that ameliorate TDP-43 pathology in mouse models of ALS.

Britt berning

research student (2017-2021)

Britt studied the role of subcellular organelle dysfunction in MND/FTD, using neuronal cell cultures and mouse models of disease.

 

SHILPA SWAMINATHAN

MASTERs StudENT, research assistant (2020-21)

Shilpa completed a summer internship and Masters coursework with the lab, followed by Masters of Molecular Biology in 2021, using cell culture systems to understand TDP-43 aggregation.

dR aMANDA wRIGHT

pOSTDOCTORAL fELLOW (2016-18)

Amanda ocused on molecular studies of Alzheimer's Disease. Amanda continues to collaborate with us on projects focused on developing MND treatments.

dR pRACHI mEHTA

pOSTDOCTORAL fELLOW (2016-18)

Prachi developed approaches for proteomics analysis of mouse tissues and identified potential biomarkers of disease.

Winonah RiddeLL

Summer Student, Research Assistant (2017-18)

Winonah joined the lab as a summer scholar, learning a variety of skills in biochemistry and histology, and continued with us to support our mouse model studies. 

 

Owen Watson

Rotation student, Research Assistant (2017-18)

Owen joined the lab for a Master of Research rotation, and continued on using his histology skills analysing brain and spinal cord tissues.

Dr Kelly Jacobs

Research Assistant (2017-18)

Kelly assisted us in drug delivery and behavioural studies of mice, as a side-project while completing her PhD studies.

DR Sheng Le

 pOSTDOCTORAL fELLOW (2017)

Sheng spearheaded pre-clinical MND/FTD mouse studies, and made a successful move to advance his career in industry.

HOSSAI GUL

MASTERS STUDENT (2017)

Hossai completed a Masters of Research project focused on uncovering disease mechanisms in genetically modified MND mice.

 

Internship and winter/summer studentsHIPS

Louis See Han Lim (Winter 2024)

Christopher Hau (Summer 2024)

Sarah Ellis (Summer 2024)

Yvonne Un (Summer 2022-23)

Yi Jia (Celine) ChYE (Summer 2022-23)

Sarah Risby-Jones (Summer 2021-22)

Joseph McAneney (Summer 2020-21)

christine xie-Nguyen (summer 2020-21)

Imaan Ahmed (Summer 2019-20)

Dr Josh (Hoi Ki) Tam (2018-2019)

Yi kit Chui (winter 2019)

Dr Yasith Mathangasinghe (intern 2019)

Giulia Del Rosso (intern 2018)

Riley Woerner (winter 2018)

Gemma Howdle (summer 2017-18)