See research from the lab on Google Scholar.

Everyone is very welcome to be in touch to request free full-text copies of any of our publications (payments are not required to journals and any such payments do not support us or our research). Please contact us directly if you are unable to locate copies of our work online and we will be happy to send you a copy.

Recent highlights

A transient protein folding response targets aggregation in the early phase of TDP-43-mediated neurodegeneration

San Gil R, Pascovici D, Venturato J, Brown-Wright H, Mehta P, Madrid San Martin L, Wu J, Luan W, Chui YK, Bademosi AT, Swaminathan S, Naidoo S, Berning BA, Wright AL, Keating SS, Curtis MA, Faull RLM, Lee JD, Ngo ST, Lee A, Morsch M, Chung RS, Scotter E, Lisowski L, Mirzaei M, Walker AK

Nature Communications, 15: 1508 (2024)

Early activation of cellular stress and death pathways caused by cytoplasmic TDP-43 in the rNLS8 mouse model of ALS and FTD

Luan W, Wright AL, Brown-Wright H, Le S, San Gil R, Madrid San Martin L, Ling K, Jafar-Nejad P, Rigo F, Walker AK

Molecular Psychiatry, 28: 2445 (2023)

Aggregation-prone TDP-43 sequesters and drives pathological transitions of free nuclear TDP-43

Keating SS, Bademosi AT, San Gil R*, Walker AK*

Cellular and Molecular Life Sciences, 80: 95 (2023) (*co-corresponding)

TDP-43 pathology: from noxious assembly to therapeutic removal (review)

Keating SS, San Gil R, Swanson MEV, Scotter EL, Walker AK

Progress in Neurobiology, 211: 102229 (2022)

If you face a paywall at the link above, the accepted article is available here

Riluzole does not ameliorate disease caused by cytoplasmic TDP-43 in a mouse model of amyotrophic lateral sclerosis

Wright AL, Della Gatta PA, Le S, Berning BA, Mehta P, Jacobs KR, Gul H, San Gil R, Hedl TJ, Riddell WR, Watson O, Keating SS, Venturato J, Chung RS, Atkin JD, Lee A, Shi B, Blizzard CA, Morsch M, Walker AK

European Journal of Neuroscience, 54: 6237 (2021)